There's certainly no lack of self-publishing options these days. But how do you know which service to pick or how to maximize the results? This post on the MediaShift blog does an excellent job summarizing six key points to consider when self-publishing. I particularly like the point that, "you are, effectively, becoming a publisher", which brings with it all the pros and cons of calling the shots.
Another important point is that, "If you're looking for a quick buck, writing a book is not the way to go", and that, "a book has the highest status but the lowest return." These harsh but generally true points were made by Stephanie Gunning, creator of 7 Quick and Easy Steps to Write and Sell Your First Book Proposal.
Item #6 though, "Get your name out there", is by far the most important bit of advice, IMHO. It's all about one of my favorite subjects, author platform. It's well summed up by this excerpt: "Publicity still remains the biggest obstacle for self-published writers -- yet there's never been a time when self-promoting a book has been easier. While you might not be able to book any television appearances on the strength of your print-on-demand book, the Internet presents myriad opportunities for the dedicated self-promoter."